Product Name :
Plectin Recombinant Rabbit Monoclonal Antibody [SY29-04]
Predicted band size :
Observed band size :
Synonyms:
EBS1 antibody EBSO antibody HD1 antibody Hemidesmosomal protein 1 antibody PCN antibody pleC antibody PLEC_HUMAN antibody PLEC1 antibody PLEC1b antibody Plectin 1 antibody 展开
Function :
Plectin is a giant protein found in nearly all mammalian cells which acts as a link between the three main components of the cytoskeleton: actin microfilaments, microtubules and intermediate filaments. Plectin links the cytoskeleton to junctions found in the plasma membrane that structurally connect different cells. By holding these different networks together, plectin plays an important role in maintaining the mechanical integrity and viscoelastic properties of tissues. Plectin binds both Lamin B and vimentin, and this binding is regulated by a variety of protein kinases. Phosphorylation by PKA or PKC results in decreased binding to Lamin B, and phosphorylation by PKA enhances the plectin-vimentin interactions.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human Plectin aa 2-101 / 4,684.1346245-52-0 web
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P, IP, IF-Tissue, IF-Cell
Coupling :
unconjugated
Clone number:
SY29-04
RRID:
AB_3069783
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.2-Aminoacetamide Data Sheet Aliquot store at -20℃ or -80℃.PMID:33663328 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 532 kDa
Positive control :
Human skeletal muscle tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue, HeLa.